The action of drugs on the human uterus: tocograph studies.

Investigation of the Relationship of Some Antihypertensive Drugs with Oxidant/Antioxidant Parameters and DNA Damage on Rat Uterus Tissue

Molecular dynamics simulation and docking studies on the binding properties of several anticancer drugs to human serum albumin

Disposition and transportation of anticancer drugs by human serum albumin (HSA) affects their bioavailability, distribution and elimination. In this study, the interaction of a set of anticancer drugs with HSA was investigated by molecular dynamics and molecular docking simulations. The drugs' activities were analyzed according to their docking scores, binding sites and structural descriptors. ...

Spasmolytic Activity of Piper Nigrum Fruit Aqueous Extract on Rat Non-Pregnant Uterus

Black pepper ( Piper nigrum ) from Piperaceae and its main ingredient (piperine) reduces gastric emptying in rats. In Iranian traditional medicine, black pepper is used to relief the menorrhalgia in women. The aim of this study was to investigate the effect of black pepper fruit aqueous extract on non-pregnant rat uterus contractions and the mechanism(s) of its action. To prepare the extract, b...

P-229: Uterine Transplantation, Is It A Promising Technique in Future?

Background: Uterine factor infertility (UFI) refers to the refractory causes of female infertility stemming from the anatomical or physiological inability of a uterus to sustain gestation. Today, uterine factor infertility affects 3-5% of the population. Traditionally, although surrogacy and adoption have been the only viable options for females affected by this condition, the uterine transplan...

Addressing the Needs of Sexual Partners of People Who Inject Drugs through Peer Prevention Programs in Iran

Despite the fact that HIV epidemic is mainly driven by injection drug use in Iran, partners of People Who Inject Drugs (PWID) have been seriously neglected in terms of effective preventive interventions. Currently, sexual partners of PWID might have access to some harm reduction services at Voluntary Counselling and Testing (VCT) centers; however, their needs have not been effectively targeted ...